Biosignatures Limited

William Michael Dracup

Patent numbers 7747048 and 7747049. notification of addition to or amendment of charge.

The North East Growth 500 Plus LP, as Security Trustee

The patent applications: us 11/212478, wo 2007/010199A1, us 11/212479, wo 2007/010198A1, us 11/212477 and wo 2007/010194A1 and any other registered intellectual property rights of the charging company.

All monies due or to become due from the charging company to the lenders on any account whatsoever under the terms of the aforementioned instrument creating or evidencing the charge

The North East Growth 500 Plus LP, as Security Trustee

Excluded property: the lease of nonlinear's premises at keel house, garth heads, newcastle upon tyne;. Fixed and floating charge over the undertaking and all property and assets including goodwill, uncalled capital, plant & machinery, equipment.. See image for full details.

All monies due or to become due from the charging companies to the lenders on any account whatsoever under the terms of the aforementioned instrument creating or evidencing the charge

Alison Morgan

Fixed and floating charge over the undertaking and all property and assets present and future, including goodwill, book debts, uncalled capital, buildings, fixtures, fixed plant & machinery see image for full details.

All monies due or to become due from the company to the chargee on any account whatsoever under the terms of the aforementioned instrument creating or evidencing the charge

Clydesdale Bank PLC

Fixed and floating charge over the undertaking and all property and assets present and future, including goodwill, book debts, uncalled capital, buildings, fixtures, fixed plant & machinery see image for full details.

All monies due or to become due from the company to the chargee on any account whatsoever

Barclays Bank PLC

Fixed and floating charges over the undertaking and all property and assets present and future including goodwill bookdebts uncalled capital buildings fixtures fixed plant and machinery.

All monies due or to become due from the company and/or all or any of the other companies named therein to the chargee on any account whatsoever