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Nucleome Therapeutics Limited

12109297

active
ltd
england wales
Companies House
Health Score
70 / 100

Some Concerns

30/30
Filing
0/30
Financial
40/40
Risk
  • Current liabilities exceed current assets (-10)
  • Going concern doubt noted in accounts (-10)

Details

Nucleome Therapeutics Limited, Inventa, Botley Road, Oxford, OX2 0HA
Incorporated 17/07/2019

Compliance

Last accounts

31/12/2025

small

Next accounts due

30/09/2027

On track

Confirmation statement

Last: 16/08/2026

Due 30/08/2027

On track

Industry

72110
Research and experimental development on biotechnology

Officers

James Raymond Hughes

director · Since 17/07/2019

ASSOCIATE PROFESSOR AT UNIVERSITY OF OXF

BRITISH,IRISH · UNITED KINGDOM

Dr Jonathan Paul Hepple

director · Since 30/11/2020

VENTURE CAPITALIST

BRITISH · UNITED KINGDOM

Also on 1 other board

Dr Rana Abdul Raouf Al-Hallaq

director · Since 21/10/2022

PARTNER, PFIZER VENTURES EXECUTIVE DIREC

AMERICAN · UNITED STATES

Also on 1 other board

Dr Bauke Anninga

director · Since 21/10/2022

VENTURE CAPITALIST

DUTCH · NETHERLANDS

Also on 1 other board

Dr Russell George Greig

director · Since 06/09/2023

CHAIR

AMERICAN,BRITISH · UNITED STATES

John Davis

director · Since 15/02/2024

PHYSICIAN

AMERICAN · UNITED STATES

Mark Bodmer

director · Since 24/07/2024

CEO

BRITISH · UNITED KINGDOM

Dr Nadiya Ishnazarova

director · Since 04/12/2025

RUSSIAN · NETHERLANDS

James Raymond Hughes

director · Since 17/07/2019

British,Irish · United Kingdom

Jonathan Paul Hepple

director · Since 30/11/2020

British · United Kingdom

Bauke Anninga

director · Since 21/10/2022

Dutch · Netherlands

Rana Abdul Raouf Al-Hallaq

director · Since 21/10/2022

American · United States

Russell George Greig

director · Since 06/09/2023

American,British · United States

John Davis

director · Since 15/02/2024

American · United States

Mark Bodmer

director · Since 24/07/2024

British · United Kingdom

Nadiya Ishnazarova

director · Since 04/12/2025

Russian · Netherlands

Former

Lachlan Tom Mackinnon

director · Resigned 16/10/2020

Danuta Mariola Jeziorska

director · Resigned 19/04/2024

Phil Boyd

secretary · Resigned 26/07/2024

Fiona Caroline Maclaughlin

director · Resigned 04/12/2025

Emma Johnson

director · Resigned 04/12/2025

Persons with Significant Control

Oxford Science Enterprises Plc

25–50% votes

Reg: 09093331 · Companies House · Corporate

Notified 02/08/2019

Former PSCs

James Raymond Hughes

Ceased 29/07/2019

Change History

status → active
2026-08-23

Active

type → ltd
2026-08-23

Private Limited Company

address line1 → Nucleome Therapeutics Limited, Inventa
2026-08-23

NUCLEOME THERAPEUTICS LIMITED, INVENTA

post town → Oxford
2026-08-23

OXFORD

officer appointed → AL-HALLAQ, Rana Abdul Raouf, Dr
2026-08-23
officer appointed → ANNINGA, Bauke, Dr
2026-08-23
officer appointed → BODMER, Mark
2026-08-23
officer appointed → DAVIS, John
2026-08-23
officer appointed → GREIG, Russell George, Dr
2026-08-23
officer appointed → HEPPLE, Jonathan Paul, Dr
2026-08-23
officer appointed → HUGHES, James Raymond
2026-08-23
officer appointed → ISHNAZAROVA, Nadiya, Dr
2026-08-23

CompanyRankvs 583+ SIC 72110 peers
61

Financial strength56th percentile among SIC peers · 14/25
Employees99th percentile among SIC peers · 15/15
LiquidityCurrent ratio 8.09× · 20/20
Longevity7 years trading (max 15) · 7/15
Filing complianceAll filings up to date · 15/15
Going concern doubt -10
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How is this score calculated?
Financial strength14/25 pts

Net worth compared to all companies in the same SIC code with published accounts. Top quartile earns the full 25 points.

Employees15/15 pts

Workforce size relative to sector peers from the most recent accounts. A larger team generally signals commercial scale.

Liquidity20/20 pts

Current assets ÷ current liabilities. A ratio above 2× earns full marks; between 1–2× scores partially; below 0.5× scores minimal points.

Longevity7/15 pts

One point per year of operation since incorporation, capped at 15. Older companies have a proven track record.

Filing compliance15/15 pts

Full 15 points when both annual accounts and confirmation statement are filed on time. Points are deducted for each overdue filing.

Risk deductions

Going concern doubt: -10 pts

Maximum score is 100. Deductions apply for insolvency history, outstanding charges, going concern doubt, or disqualified officers.

Going Concern Doubt

directors have identified that timing and successful completion of the planned funding represents a material uncertainty that may cast significant doubt on the company's ability to continue as a going concern. However, whilst noting this material uncertainty, the directors are of the opinion that it is appropriate to adopt the going concern basis in the preparation of the financial statements due

Key FinancialsYear ending 31/12/2025

Net Worth

£1k

Balance sheet strength

Cash

£7.7M

Cash in the bank

Net Current Assets

£10.2M

Working capital

Current Assets

£11.7M

Current Liabilities

£1.4M

Fixed Assets

£1.2M

Debtors

£4.0M

44avg. employees

Balance Sheet

Intangible assets£55k
Assets less current liabilities£11.4M
Prepared with IRIS Accounts Production

EstimatesDerived

YearCurrent Ratio
20258.09

Derived from filed accounts. Not audited figures.